"Kids used to make fun of my voice growing up, but who's laughing now? For the last month, an entire country was blowing Vuvuzela," Ferrell quipped.
"I'm the most popular sound in the world!" Ferrell continued. "My real passion is music. I just recorded an album with the amazing Janelle Monae. Janelle, lets do track 40. Gotta give the people what they want!"
Monae then dueted with Ferrell on a "Jeff Vuvuzela remix" of Roberta Flack's 'Tonight I Celebrate My Love,' before kissing and taking a bow.
Watch the video after the jump.