The rapper's private plane had to make an emergency landing in Texas so he could be rushed to the hospital, TMZ reported.
Lil Wayne was released after spending several hours under close watch. As of press time, no diagnosis has been announced to the public.
The MC, who turned 30 last month, had a brief stint in a St. Louis, Mo. hospital after putting a gash above his left eye during a skateboarding accident in 2011.
See Hip-Hop's Most Expensive Album Covers Valued by a Jeweler